منابع مشابه
Estrogens, progestins, and atherosclerosis.
To the Editor: We feel compelled to comment on the Brief Review “Should progestins be blamed for the failure of hormone replacement therapy to reduce cardiovascular events in randomized controlled trials?” by Koh and Sakuma.1 Specifically, although we agree with the suggestion that the effects of estrogen on the vasculature may depend on the extent and severity of existing atherosclerosis, we d...
متن کاملEstrogens, Progestins, and Atherosclerosis
To the Editor: We feel compelled to comment on the Brief Review “Should progestins be blamed for the failure of hormone replacement therapy to reduce cardiovascular events in randomized controlled trials?” by Koh and Sakuma.1 Specifically, although we agree with the suggestion that the effects of estrogen on the vasculature may depend on the extent and severity of existing atherosclerosis, we d...
متن کاملEstrogens, Progestins, and Atherosclerosis
To the Editor: We feel compelled to comment on the Brief Review “Should progestins be blamed for the failure of hormone replacement therapy to reduce cardiovascular events in randomized controlled trials?” by Koh and Sakuma.1 Specifically, although we agree with the suggestion that the effects of estrogen on the vasculature may depend on the extent and severity of existing atherosclerosis, we d...
متن کاملEstrogens and atherosclerosis.
Numerous epidemiological as well as experimental studies have suggested that estradiol (E2) prevents atherosclerosis development. However two controlled prospective and randomized studies in women using hormone replacement therapy (HRT) did not confirm this beneficial effect. We then decided to use mouse models of atherosclerosis to define the possible mechanisms involved and the reasons for th...
متن کاملEstrogens, Progestins, and Specific Estrogen Receptor Modulators (SERMs)
Biologically important natural estrogens and progestins include estradiol, estrone, estriol, and progesterone. Estradiol-17 is the most potent estrogen that is found naturally in women. Estrone is one-tenth as biologically active as estradiol, and estriol is the weakest of the three. Estriol is synthesized by the placenta and is excreted at high levels in the urine of pregnant women. Progestero...
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ژورنال
عنوان ژورنال: Arteriosclerosis, Thrombosis, and Vascular Biology
سال: 2004
ISSN: 1079-5642,1524-4636
DOI: 10.1161/01.atv.0000146176.62463.87